Therapeutic Influence Of Concomitant Disease

Existing disease states can influence drug therapy. Patients with decreased renal function require appropriate dose adjustments. The use of NSAIDs requires additional care and monitoring of patients with decreased renal function (72,112-115) or with compromised cardiovascular function. If patients are taking antihypertensive medications such as angiotensin-converting enzyme inhibitors and diuretics, the use of NSAIDs can interfere with their pharmacological effects (116-122). Also, patients with cardiovascular disease such as congestive heart failure requires special care for the use of NSAIDs because, in this patient population, they are most susceptible to the decreased renal perfusion effect associated with NSAIDs (123-126).

Blood Pressure Health

Blood Pressure Health

Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...

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