Surgical implications

Surgery on patients with disordered haemopoiesis is fraught with potential complications. Anaemic patients have hypoxic tissues with deranged function, reduced numbers of granu-locytes results in impaired inflammation and wound healing, reduced numbers of phagocytes and lymphocytes make the patients prone to bacterial, viral and parasitic infections, and thrombocytopaenia leads to a bleeding tendency. The outcome of surgery can be improved by transfusing the appropriate blood product peri-operatively. Transfusion of stem cells, bone marrow, fresh whole blood, packed red blood cells, neutrophil concentrates or platelet concentrates should be appropriately timed either pre-, intra- or postoperatively to achieve the optimal effect.

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