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Figure 25.1. (A) Survival curves of the normal-lived Ra strain and of two long-lived strains (La and 2La) sequentially derived from it by a direct selection for delayed female fecundity. Each survival curve is based on the age-specific values obtained from two or three replicate cohorts consisting of at least 250 mixed sex individuals each. The Ra, La and 2La curves are significantly different (log-rank test = 530.16, df = 2, P < 0.0001). See Arking et al. (2000a) for experimental details. (B) Survival curves of the normal-lived Ra strain and the PQR strain selected from it by direct selection for paraquat resistance. Each survival curve is based on the age-specific values obtained from mixed sex cohorts of 250-450 animals each. The two curves are significantly different (log-rank test = 24.76, df = 1, P < 0.00005). See Vettraino et al. (2001) for experimental details. (C) Survival curves of the normal-lived Ra control strain and the longer-lived Ra heat-treated strain. The animals were subjected to a nonlethal heat shock (37°C for 90 minutes) early in life at days 5-7 after eclosion. They were then maintained under controlled optimal conditions, and their survival was monitored. The two curves are significantly different (log rank test = 17.84, df = 1, P < 0.00005). See Keuther and Arking (1999) for experimental details. (After Arking et al., 2002)

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