Longer Life Expectancy In Organisms Belonging To The Same Cohort Group Is Associated With Relatively Higher Levels Of Antioxidants And Lower Concentrations Of The Products Of Oxygen Free Radical Reactions

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All houseflies lose the ability to fly prior to death. Therefore, in an aging population, shorter-lived flies can be identified as flightless ''crawlers'' in contrast to their longer-lived cohorts, the ''fliers.'' The average lifespan of crawlers is about one-third shorter than the fliers. Levels of antioxidant defenses (superoxide dismutase (SOD), catalase (CAT), and glutathione) and products of

ETC activity oxygen free radical reactions (inorganic peroxides and thiobarbituric acid [TBA]-reactants) were compared between crawlers and fliers. The fliers showed greater SOD and CAT activities and glutathione concentrations than crawlers, whereas the amount of inorganic peroxides (H2O2) and TBA-reactants was higher in the crawlers than in fliers (Sohal et al., 1986).

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Anti Aging Made Easy

Anti Aging Made Easy

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