A variety of techniques for the study of telomere biology are available, including telomere terminal restriction fragment (TRF) analysis, fluorescence in situ hybridization (FISH), variations of polymerase chain reaction (PCR), and the telomere repeat amplification protocol (TRAP). For an excellent summary of selected methods utilized to measure telomere length, see Nakagawa et al., (2004). A list of references pertaining to techniques used in the study of telomere biology is contained in Table 29.4.
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