Definition

HHT, also known as Osler-Weber-Rendu disease, is a fairly common autosomal-dominant condition characterized by telangiectases of the dermis and mucous membranes and visceral arteriovenous malformations (AVMs). HHT was first reported in 1864 by Sutton and was named in 1909 by Hanes, who first described its histologic features. The triple eponymous title, Osler-Weber-Rendu, draws its name form Henri Rendu, Sir William Osler, and Frederick Weber, who published remarkably descriptive and accurate case reports of the disease at the turn of the last century (10).

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