Glucagon-secreting tumors of the pancreatic islets (glucagonomas) produce a distinctive syndrome characterized by the development of prominent mucocutaneous findings, adult-onset diabetes mellitus, weight loss, and anemia (18). Becker initially described the constellation of symptoms associated with an islet tumor of the pancreas in 1942.
The cutaneous component of this syndrome, termed necrolytic migratory erythema (NME), was first described by Wilkinson in his report of a patient with pancreatic carcinoma in 1973. The full syndrome was finally described by Mallison in 1974 in his review of nine patients with glucagon-secreting tumors.
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All you need is a proper diet of fresh fruits and vegetables and get plenty of exercise and you'll be fine. Ever heard those words from your doctor? If that's all heshe recommends then you're missing out an important ingredient for health that he's not telling you. Fact is that you can adhere to the strictest diet, watch everything you eat and get the exercise of amarathon runner and still come down with diabetic complications. Diet, exercise and standard drug treatments simply aren't enough to help keep your diabetes under control.