The sickle cell trait offers genetic protection against Plasmodium falciparum, which is endemic in West Africa. Due to the trans-Atlantic slave trade and subsequent global migration, the trait has been distributed throughout the Western hemisphere. Sickle cell anemia affects up to 8% of African Americans. The majority of these patients have sickle cell trait. Sickle cell disease affects approximately 0.2% of African Americans. The prevalence of sickle cell disease in non-African Americans is approximately 0.08% (10,11).
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.