Pathogenesis

While sarcoidosis has an unknown etiology, it is postulated to result from exposure to environmental agents in a genetically susceptible host. This hypothesis is supported by racial differences and clusters of disease, implying a genetic predisposition, and the immunophenotype of an antigen-driven response with restricted T-cell receptor usage. Studies throughout the world reveal different genetic associations depending on ethnicity; the most commonly associated genes are class I HLA-A1 and -B8 and class II HLA-DR3. The mode of inheritance is likely polygenic (30,32).

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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