The cause of SS is unknown, but several stages of its pathogenesis are being elucidated. The initial event may be activation of ductal epithelial cells by an unknown antigen. Expression of co-stimulatory molecules [i.e., HLA-DR, CD80, CD86, intracellular adhesion molecule (ICAM)] by ductal epithelium highlights an unexpected role in the regulation of the immune response. Affected organs exhibit periductal lymphocytic infiltrates composed initially of CD4+ T-cells, which can subsequently attract B-cells. The T-cells release cytokines

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10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

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