SJS is a severe illness with significant morbidity and mortality. It is characterized by an abrupt onset of mucocutaneous necrosis of at least two mucosal sites with variable skin involvement, following a characteristic prodrome of a respiratory illness. Most commonly, SJS is drug-induced, but many causative factors have been implicated. Treatment consists of supportive care and discontinuation of the offending agent; administration of corticosteroids or IVIG is controversial and not evidence-based. Please see Chapter 22 for further discussion of SJS.
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The term vaginitis is one that is applied to any inflammation or infection of the vagina, and there are many different conditions that are categorized together under this ‘broad’ heading, including bacterial vaginosis, trichomoniasis and non-infectious vaginitis.