Co2 H2o H Hco76

As protons are produced in this reaction, venous blood has a somewhat lower pH (7.2) than arterial (7.6), even though the effect is mitigated by the buffering capacity of blood. This is important, because a drop in pH lowers the affinity of haemoglobin for oxygen, and increases that for bicarbonate. This is called the BoHR-effect1. Haemoglobin actually releases one proton for each molecule of oxygen bound, thus decreasing pH interferes with oxygen binding.

Bohr-effect s? o

Bohr-effect

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