Other Soluble Factors

There are additional soluble factors in saliva, which have been shown to have antiCandida activity. Earlier work had reported that lysozyme in parotid saliva was increased in relation to the oral Candida load (Yeh et al., 1997) though the pathway of such stimulation was not identified. Statherin mediates a dose-dependent adhesion of C. albicans to epithelial cells (Johansson et al., 2000). This adhesion could be inhibited by specific IgG antibodies to statherin, suggesting that antibodies derived from the gingival crevice could be active in vivo. Other workers have suggested that complement factors may have a role in homeostasis of Candida. Triebel et al. (2003) showed that in normal sera containing complement factors that Sap activity was reduced, growth of Candida was reduced, and phagocytosis was enhanced. However, these results suggest that in vivo these could only be active around the gingival crevice and might explain why this is not a favourite site for Candida colonisation.

How To Cure Yeast Infection

How To Cure Yeast Infection

Now if this is what you want, you’ve made a great decision to get and read this book. “How To Cure Yeast Infection” is a practical book that will open your eyes to the facts about yeast infection and educate you on how you can calmly test (diagnose) and treat yeast infection at home.

Get My Free Ebook


Post a comment