When early gestation biopsy specimens were stained for potential CMV receptors, proximal cell columns did not express EGFR, but punctate staining for gB was sometimes detected at the cell surface, suggesting that virions were clustered in membranes (Maidji et al. 2007). CMV receptors expressed on cytotrophoblasts in villus explants were studied in model cell columns of anchoring villi infected with Toledorec ex vivo (Fig. 3a). Like cell columns in intact placentas, extravillous
Was this article helpful?