Aml I

29 4-7 mg/kg/d mg/m2 on days 4-7 + decamethasone 40 mg; 2-6 cycles Continuous x 7 d (q3w) + thalidomide 100-400 mg qd (from d 4) + decamethasone 40 mg qd (days 4-7; q3w) ; total 3 cycles Continuous x 10 d; + fludarabine 15-30 mg/m2/d, cytarabine 1-2 mg/m2/d on days 6-10; G-CSF 5 ^g/m2/d on days 5-10 Continuous x10 d; + daunorubicin 45-60 mg/m2/d on days 4-6, cytarabine 100 mg/m2/d on days 4-10; G-CSF 5

Fever, creatinine_, 18/33 7/33 12 m hyperglycemia

No DLT; diarrhea, 9/20 11/20 N/A fluid retention, hypocalcaemia, pancytopenia

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