Objectives

After completing this chapter, the student will be able to:

1. Recall the physiology and function of granulocytes.

2. Describe the steps involved in phagocytosis.

3. Identify conditions that cause a quantitative increase or decrease in a particular white cell line.

4. Describe the changes observed when white cells respond to infection.

5. Identify the acquired and inherited qualitative changes in the white cell.

6. Identify conditions that lead to hyposegmenta-tion or hypersegmentation of the segmented neutrophils.

7. Define the probable causes for an increased lymphocyte count.

8. Define the differences seen in an adult's versus a child's lymphocyte count.

9. Describe the effects of the human immunodeficiency virus on the complete blood count and the peripheral smear.

10. Recall the reactive symptoms of infectious mononucleosis and cytomegalovirus.

11. Define white cell-related terms such as leukocytosis, left shift, leukemoid reaction, and leukoery-throblastic reaction.

12. Briefly describe the lipid storage diseases, such as Gaucher's, Niemann-Pick, and Tay-Sachs diseases.

144 Part III • White Cell Disorders

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