Word Key

Antiglobulin test • Test used in immunohematology to determine if a patient has made an alloantibody present in the serum or an antibody that is coating the red cells

Cholelithiasis • Gallbladder disease

Crenation • Term used to describe the edges of red cells that seem to have ridges

Ecchymosis • bruising

Jaundice • Yellowish color usually seen in the mucous membranes of the eyes and noticed as an overall skin color

Prophylactic • Preventive


1. Lux SE, Becker PS. Disorders of the red cell membrane skeleton: Hereditary spherocytosis and hereditary ellip-tocytosis. In: Scriver CR, Baudet AB, Sly US, et al, eds. The Metabolic Basis of Inherited Disease, 6th ed. New York: McGraw-Hill, 1989; 2367.

2. Iolascon A, Perrotta S, Stewart GW Red blood cell membrane defects. Rev Clin Exp Haematol 7:22-56, 2003.

3. Evans EA, Waugh R, et al. Elastic area compressibility modules of red cell membrane. Biophys J 16:585, 1976.

4. Vives Corrons JL, Besson I. Red cell membrane Na+ transport system in hereditary spherocytosis relevance to understanding the increased Na+ permeability. Ann Hematol 80:535-539, 2001.

5. Panigrahi I, Rhadke SR, Agarwal A, et al. Clinical profile of hereditary spherocytosis in North India. J Assoc Phys India 50:1360-1367, 2002.

6. Payne MS. Intracorpuscular on defects leading to increased erythrocyte destruction. In: Rodak B, ed. Hematology: Clinical Principles and Applications, 2nd ed. Philadelphia: WB Saunders, 2002; 267.

7. Michaels LA, Cohen AR, Zhao H, et al. Screening for hereditary spherocytosis by use of automated erythro-cytes indices. J Pediatr 13:957-960, 1997.

8. Tamary H, Aviner S, Freud E, et al. High incidences of early cholelithiasis detected by ultrasonography in children and young adults with hereditary spherocytosis. J Pediatr Hematol Oncol 25:952-954, 2003.

9. deBuys Roessingh AS, de Laguasie P, Rohrlich P, et al. Follow up of partial splenectomy in children with hereditary spherocytosis. J Pediatr Surg 37:1459-1463, 2002.

10. Gallagher PG, Forget BD, Lux SE. Disorders of the erythrocyte membrane. In: Nathan DG, Oski SH, eds. Nathan and Oski's Hematology of Infancy and Childhood, 5th ed. Philadelphia: WB Saunders, 1998; 544-664.

11. Cattani JA, Gibson FD, Alperes MP, et al. Hereditary ovalocytosis and reduced susceptibility to malaria in Papua New Guinea. Trans R Soc Trop Med Hyg 705-709, 1987.

12. Hanspal M, Hanspal JS, Sahr KE, et al. Molecular basis of spectrin deficiency in hereditary pyropoikilocytosis. Blood 82:1652-1660, 1993.

13. Palek J. Hereditary elliptocytosis and related disorders. Clin Hematol 14:45, 1985.

14. Fricke B, Argent AC, Chetley MC, et al. The "stomatin" gene and protein in overhydrated hereditary stomatocy-tosis. Blood 102:2268-2277, 2003.

15. Stewart GW, Amess JA, Eber SW, et al. Thrombo-embolic disease after splenectomy for hereditary stoma-tocytosis. Br J Hematol 93:303-310, 1996.

16. Glader BE, Fortier N, et al. Congenital hemolytic anemia associated with dehydrated erythrocytes and increased potassium ions. N Engl J Med 291:491, 1974.

17. Fiorelli G, Martinez di Montemuros F, Capellini MD. Chronic non-spherocytic hemolytic disorders associated with glucose 6 phosphate dehydrogenase variants. Baillieres Best Pract Res Clin Haematol 13:39-55, 2000.

18. Beutler E. Red cell enzyme defects. Hematol Pathol 4:103-114, 1990.

19. Mehta A, Mason PJ, Vulliam TJ. Glucose 6 phosphate dehydrogenase. Baillieres Best Pract Res Clin Haematol 13:21-38, 2000.

20. Lazzato L. G6PD deficiency and hemolytic anemias. In: Nathan DG, Oski FA, eds. Nathan and Oski's Hematol-ogy of Infancy and Childhood, 4th ed. Philadelphia: WB Saunders, 1993; 679.

112 Part II • Red Cell Disorders

21. Valentine WN, Koyichi RT, Paglia DE. Pyruvate kinase and other enzyme deficiency disorders of the erythrocyte. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds, The Metabolic Basis of Inherited Diseases, 6th ed. New York: McGraw-Hill, 1989; 1606-1628.

22. Brown BA. Hematology: Principles and Procedures, 6th ed. Philadelphia: Lea and Febiger; 1993; 298.

23. Gordon-Smith EC, Marsh JC, Gibson FM. Views on the pathophysiology of aplastic anemia. Int J Hematol 76 (Suppl 12):163-166, 2002.

24. Trigg ME. Hematopoietic stem cells. Pediatrics 113 (Suppl 4):1051-1057, 2004.

25. Bagby GC Jr. Genetic basis of Fanconi's anemia. Curr Opin Hematol 10:68-73, 2003.

26. Schroeder-Kurth TM, Auerbach AD, Obe G. Fanconi Anemia: Clinical, Cytogenetics and Experimental Aspects. Berlin: Springer-Verlag, 1989; 264.

27. Alter BP, Young NS. The bone marrow failure syndromes. In: Nathan DG, Oski FA, eds. Nathan and Oski's Hematology of Infancy and Childhood, 4th ed. Philadelphia: WB Saunders, 1992; 263.

28. Krijanovski OI, Seiff CA. Diamond-Blackfan anemia. Hematol Oncol Clin N Am 11:1061, 1997.

29. Lawrence LW, Harmening DM, Green R. Hemolytic anemia: Extracorpuscular defects and acquired intracor-puscular defects. In: Harmening D, ed. Clinical Hematology and Fundamentals of Thrombosis, 4th ed. Philadelphia: FA Davis, 2002; 202.

30. Young NS. Paroxysmal nocturnal hemoglobinuria: Current issues in pathophysiology and treatment. Curr Hematol Rep 4:103-109, 2005.

31. Hillmen P, Lewis SM, Bressler M, et al. Natural history of PNH. N Engl J Med 333:1253-1258, 1995.

32. Meyers G, Parker CJ. Management issues in paroxysmal nocturnal hemoglobinuria. Int J Haematol 77:125-132, 2003.

33. Hill A, Hillmen P, Richards SJ, et al. Sustained response and long-term safety of eculizumab in paroxysmal nocturnal hemoglobinuria. Blood 106:2559-2565, 2005.

34. Schubert J, Alvarado M, Uciechowski P, et al Diagnosis of paroxysmal nocturnal haemoglobinuria using immunophenotyping of peripheral blood cells. Br J Haematol 79:487-492, 1991.

35. Brodsky RA, Mukhina GL, Li S, et al. Improved detection and characterization of paroxysmal nocturnal hemoglobinuria using fluorescent aerolysin. Am J Clin Pathol 114:459-466, 2000.

Copyright ©2007 byF: A. Davis.

Was this article helpful?

0 0

Post a comment