Cellular Basis Of fru Functions In Male Courtship Behavior

In neurobiology, it is critical to determine the neural circuit underlying respective behavior. It is a demanding issue to describe neural connections formed by fru-expressing neurons to illustrate the entire network that determines male courtship behavior. To this end, efforts have been made to identify individual neurons that express Fru (Billeter and Goodwin, 2004 Manoli et al., 2005 Stockinger et al., 2005). To identify fru-expressing neurons, it is crucial to obtain reporter strains that...

CV1aR in the ventral pallidum

Genetic and pharmacological tools have indeed implicated V1aR in the ventral pallidum as a modulator of social bonding behavior. Increasing the numbers of receptors in the ventral pallidum of the male prairie vole by viral vector gene transfer facilitated partner preference formation in the male prairie vole (Pitkow et al., 2001). A site-specific antagonist for the V1aR administered to the ventral pallidum prior to mating and cohabiting with a female eliminated partner preference formation in...

Sexual dimorphism in the C elegans nervous system

The sex differences exhibited by the C. elegans nervous system are of two general forms. First, and more conspicuous, is the presence of sex-specific neurons in both hermaphrodites and males (Fig. 1.2A Table 1.1). This sex-specific component of the nervous system comprises 8 neurons in hermaphrodites and 89 in males, all of which are thought to function in circuits dedicated to sexually dimorphic behavior. In both sexes, the sex-specific nervous system is overlaid onto the 294 neurons common to...