HIVassociated Pulmonary Hypertension

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Georg Friese, Mirko Steinmuller and Ardeschir Ghofrani

Pulmonary hypertension is a severe life-limiting disease, often affecting younger patients. The connection between HIV infection and the development of pulmonary hypertension is well documented (Mette 1992, Simonneau 2004). However, the underlying pathobiology still remains unclear. Given that the prognosis of HIV infection has been improved by HAART, severe pulmonary hypertension is becoming a life-limiting factor (Nunes 2002).

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