Bilberry extract 200 mg/(kg ■ day) administered intraperitoneally to euthy-roid rats increased radiolabeled triiodothyronine (T3) transport into the brain, compared to vehicle only (21). Postulated mechanisms include central or peripheral inhibition of L-thyroxine's (T4) deiodination to T3; inhibition of T3 protein binding; or enhanced T3 binding to carrier proteins in the brain capillary wall (21). Whether bilberry could interact with thyroid replacement therapy remains to be seen.

Studying a diabetic rat model, Cignarella and colleagues (1) found that administration of an extract from the leaves of blueberry plants caused a 26% reduction in plasma glucose. This was also accompanied by a 39% decrease in plasma triglycerides. Whether this reduction in glucose levels might result in a clinically significant interaction in patients taking antidiabetic agents is unknown, because the glucose lower effects have not been studied in humans. Likewise, whether the triglyceride-lowering effects of hypolipidemic agents used in humans would be enhanced by coadministration of anthocyanidins is unknown.

Berry Boosters

Berry Boosters

Acai, Maqui And Many Other Popular Berries That Will Change Your Life And Health. Berries have been demonstrated to be some of the healthiest foods on the planet. Each month or so it seems fresh research is being brought out and new berries are being exposed and analyzed for their health giving attributes.

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