Project Title Genetic Architecture Of Heart Disease In Rural Brazil

Principal Investigator & Institution Williams-Blangero, Sarah A. Scientis and Chair Southwest Foundation for Biomedical Res San Antonio, TX 782450549 Timing Fiscal Year 2001 Project Start 30-SEP-2001 Project End 31-JUL-2006 Summary (provided by applicant) This project has the ultimate goal of elucidating the genetic architecture of Chagas' disease in a population residing in rural Brazil. A leading cause of heart disease throughout Latin America, it affects between 16 and 18 million...

Project Title Cholesterol Lowering By Nurses To Control Heart Disease

Principal Investigator & Institution Blumenthal, Roger S. Johns Hopkins University 3400 N Charles St Baltimore, MD 21218 Summary The purpose of this study is to evaluate the effectiveness of a nurse-managed, case-management system of individualized lifestyle modification and pharmacologic intervention to manage lipid disorders in adults who have undergone coronary artery bypass graft surgery (CABG). Clinical trials have provided strong scientific evidence that lowering serum cholesterol will...

Project Title Subclinical Heart Disease In Insulindependent Diabetes

Principal Investigator & Institution Rewers, Marian J. Professor of Pediatrics Preventive Med and Biometrics University of Colorado Hlth Sciences Ctr P.O. Box 6508, Grants and Contracts Aurora, CO 800450508 Timing Fiscal Year 2001 Project Start 01-SEP-1999 Project End 31-AUG-2004 Summary Approximately 10 percent of premature coronary artery disease (CAD) morbidity and mortality in the general population is due to insulin dependent diabetes mellitus (IDDM). By age 55, 35 percent of IDDM...

Project Title The Clinical Utility Of Endothelial Function In Pad

Principal Investigator & Institution Vita, Joseph A. Associate Professor Boston Medical Center Gambro Bldg, 2Nd Fl, 660 Harrison Ave, Ste a Boston, MA 02118 Timing Fiscal Year 2003 Project Start 22-SEP-2003 Project End 31-AUG-2008 Summary (provided by applicant) Peripheral arterial disease (PAD) produces considerable morbidity and mortality, and the precise factors that determine disease progression and the responses to therapy remain largely unknown, In addition to their risk for critical...

Project Title Cardiovascular Health Studyechocardiography

Principal Investigator & Institution Gottdiener, John S. Medicine Georgetown University Washington, DC 20057 Timing Fiscal Year 2001 Project Start 30-JUN-1993 Project End 31-MAY-2001 Summary The Cardiovascular Health Study is a population-based, longitudinal study of risk factors for the development and progression of coronary heart disease and stroke in adults over the age of 65 years. Both risk factors established in middle-aged population and suspected risk factors are examined and...