The Autonomic Nervous System

• Cocaine as a sympathomimetic drug

• Synapses en passant

Sympathetic and parasympathetic axons release different neurotransmitters (fig. 9.9)

Varicosity

Smooth muscle cell

Varicosity

Smooth muscle cell

Sympathetic neuron

Synapses en passant

Parasympathetic neuron

Sympathetic neuron

Synapses en passant

Parasympathetic neuron

Axon of Sympathetic Neuron

Synaptic vesicle with norepinephrine (NE)

Axon of Sympathetic Neuron

Synaptic vesicle with norepinephrine (NE)

Adrenergic receptors

Smooth muscle cell

Adrenergic receptors

Antagonistic effects Cholinergic receptors

Smooth muscle cell

Antagonistic effects Cholinergic receptors

Axon of Parasympathetic Neuron

Synaptic vesicle with acetylcholine (ACh)

Axon of Parasympathetic Neuron

Synaptic vesicle with acetylcholine (ACh)

• The receptors involved in autonomic regulation (fig. 9.10)

• Comparison of nicotinic and muscarinic receptors (fig. 9.11)

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