The liver regulates the chemical composition of the blood in numerous ways. In addition, the liver produces and secretes bile, which is stored and concentrated in the gallbladder prior to its discharge into the duodenum.The pancreas produces pancreatic juice, an exocrine secretion containing bicarbonate and important digestive enzymes, which is passed into the duodenum via the pancreatic duct.
The liver is positioned immediately beneath the diaphragm in the abdominal cavity. It is the largest internal organ, weighing about 1.3 kg (3.5 to 4.0 lb) in an adult. Attached to the inferior surface of the liver, between its right and quadrate lobes, is the pear-shaped gallbladder. This organ is approximately 7 to 10 cm (3 to 4 in.) long. The pancreas, which is about 12 to 15 cm (5 to 6 in.) long, is located behind the stomach along the posterior abdominal wall.
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