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Figure 7 The evolutionary relationship between sunlight and the amino-acid tryptophan and its major derivatives serotonin, melatonin, auxin and NADH. In addition, the connections of certain tryptophan containing proteins are illustrated chlorophyll, rhodopsin and 5-HT1A receptor. These relationships began in the earliest eukaryotic cells and continue in humans. means of converting sunlight into biological energy. In the simplest cells, in the presence of sunlight, serotonin and related...

Collaborative Organization

Figure 6 The progression of 5-HT neurons from aplysia to humans. In the aplysia nervous system there are only a few neurons which contain serotonin, and these neurons are large, with extensive connections. In the rodent brain, the 5-HT neurons are arranged in large grouping along the midline of the mes-cencephalon. The axons from these neurons ascend towards the forebrain in large bundles using mainly the ancient medial fore-brain bundle. In primates, the distribution of serotonergic neurons in...

Dri

DPAG (inhibition of fight escape) Q RVLM (inhibition of sympathetic activity) mPFC, Acb, BL, vHPC, CE, BNST, DA, LC, LPB (anxiety-related behavior) mPFC, dHPC, vHPC (coping, resilience) Plate 10 Diagrammatic illustration of the topographical distribution of serotonergic neurons projecting to functionally related forebrain and hindbrain targets in the rat brain. Serotonergic neurons projecting to the caudate putamen and substantia nigra (blue) are located predominantly in the rostral part of the...