Hepatitis C is a blood-borne infection, transmitted through contaminated blood, injection drug use equipment, and, less efficiently, through sexual intercourse. Prevalence of hepatitis C among the HIV-infected population is about 30% worldwide, but can vary from 10.4% in an Asian Pacific cohort (TREAT Asia HIV Observational Database) (20) to 51% in a largely injection drug use population in Columbia, Canada (21). In the United States and Europe, estimates are that 25% of HIVpositive individuals have hepatitis C infection as well. More recently, acute hepatitis C
outbreaks are being reported among men who have sex with men (21, 22). Hepatitis C infection has emerged as an important cause of morbidity and mortality concomitant with the decline in HIV-related morbidity and mortality associated with effective antiretroviral treatment.
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